Aminoleban® EN powder:

The Oral Nutrient for Your Liver

Aminoleban® EN powder is an oral nutritional supplement that contains carbohydrates, fats, vitamins, minerals, amino acids and other elements. It is suitable for people concerned about nutritional deficiencies and liver health1. Provided by Otsuka Pharmaceutical (H.K.) Ltd., Aminoleban® EN powder is an oral nutrient for liver registered with Hong Kong Department of Health. For enquiry, please consult your doctor or pharmacist.

Aminoleban® EN powder:

The Oral Nutrient for Your Liver

Aminoleban® EN powder is an oral nutritional supplement that contains carbohydrates, fats, vitamins, minerals, amino acids and other elements. It is suitable for people concerned about nutritional deficiencies and liver health1. Provided by Otsuka Pharmaceutical (H.K.) Ltd., Aminoleban® EN is an oral nutrient for liver registered with Hong Kong Department of Health. For enquiry, please consult your doctor or pharmacist.

What is Aminoleban® EN powder?

50 g per aluminium package
21’s per Aminoleban® EN powder carton

Providing branched chain amino acids and micronutrients that the human body needs1 Proteins in the human body are composed of 20 types of amino acids: 9 types of essential amino acids and 11 types of non-essential amino acids. Essential amino acids cannot be synthesised by the human body and need to be taken from diets. Three of the nine essential amino acids are called branched chain amino acids (BCAA), which are leucine, isoleucine, and valine2.

What is Aminoleban® EN powder?

50 g per aluminium package
21’s per Aminoleban® EN powder carton

Providing branched chain amino acids and micronutrients that the human body needs1 Proteins in the human body are composed of 20 types of amino acids: 9 types of essential amino acids and 11 types of non-essential amino acids. Essential amino acids cannot be synthesised by the human body and need to be taken from diets. Three of the nine essential amino acids are called branched chain amino acids (BCAA), which are leucine, isoleucine, and valine2.

Aminoleban® EN powder has been proven effective in clinical studies to:

Aminoleban® EN powder has been
proven effective in clinical studies to:

Improve serum protein levels3

Serum protein level showed a consistent tendency to increase from the 2nd week to the 3rd month. The effect was particularly pronounced, reaching statistically significant improvement throughout the entire period from the 3rd month to the 6th month.

Improve serum protein levels3

Serum protein level showed a consistent tendency to increase from the 2nd week to the 3rd month. The effect was particularly pronounced, reaching statistically significant improvement throughout the entire period from the 3rd month to the 6th month.
Karnofsky’s performance status can be scored from Grade 0 to 10. Generally speaking, Grade 3 or higher means that the patient’s normal daily life more or less require assistance, while Grade 2 or lower means the patient’s daily life does not require assistance.

Improve functional performance3

The condition of some patients was improved from Grade 3 or higher to Grade 2 or lower after treatment. This improvement was significant after treatment for 2 weeks, and continued to be so until the end of the 6-month study period.

Improve functional performance3

The condition of some patients was improved from Grade 3 or higher to Grade 2 or lower after treatment. This improvement was significant after treatment for 2 weeks, and continued to be so until the end of the 6-month study period.

Karnofsky’s performance status can be scored from Grade 0 to 10. Generally speaking, Grade 3 or higher means that the patient’s normal daily life more or less require assistance, while Grade 2 or lower means the patient’s daily life does not require assistance.

Improve quality of life3

Improvement in Karnofsky’s performance status was significant after treatment for 2 weeks, and continued to be so until the end of the 6-month study period.

Improve quality of life3

Improvement in Karnofsky’s performance status was significant after treatment for 2 weeks, and continued to be so until the end of the 6-month study period.

How to take Aminoleban® EN powder?1

Ingest with meals three times a day for adults usually

The dosage may be adjusted according to the age of the patient and severity of symptoms

How to take Aminoleban®
EN powder
?1

Ingest with meals three times a day for adults usually

The dosage may be adjusted according to the age of the patient and severity of symptoms

Preparation of Aminoleban® EN powder1

Blender

Pour about 180 mL of water or warm water into a blender, add the entire contents of one Aminoleban® EN powder package (50 g) into it.

Thoroughly reconstitute

The volume of the reconstitution is approximately 200 mL, and the reconstitution provides about 1 kcal/mL of energy

Aminoleban® EN powder Shaker

Pour about 180 mL of water or warm water into the Aminoleban® EN powder Shaker

Add the entire contents of one Aminoleban® EN powder package (50 g) into it. Close the lid and thoroughly shake it until the powder dissolves

The volume of the reconstitution is approximately 200 mL, and the reconstitution provides about 1 kcal/mL of energy

Preparation of
Aminoleban® EN powder
1

Blender

Pour about 180 mL of water or warm water into a blender, add the entire contents of one Aminoleban® EN powder package (50 g) into it.

Thoroughly reconstitute

The volume of the reconstitution is approximately 200 mL, and the reconstitution provides about 1 kcal/mL of energy

Aminoleban® EN powder Shaker

Pour about 180 mL of water or warm water into the Aminoleban® EN powder Shaker

Add the entire contents of one Aminoleban® EN powder package (50 g) into it. Close the lid and thoroughly shake it until the powder dissolves

The volume of the reconstitution is approximately 200 mL, and the reconstitution provides about 1 kcal/mL of energy

Important precautions1

This product is intended for oral feeding and should not be administered into a blood vessel

This product should be reconstituted before use (within 10 hours). If necessary, the preparation should be stored in a cool place

Flavors and fibrous vegetables may be mixed with the preparation to improve palatability

Important precautions1

This product is intended for oral feeding and should not be administered into a blood vessel

This product should be reconstituted before use (within 10 hours). If necessary, the preparation should be stored in a cool place

Flavors and fibrous vegetables may be mixed with the preparation to improve palatability

Appropriate energy and protein intake

Excessive protein and energy intake is one of the main causes of high blood ammonia levels. On the contrary, insufficient protein and energy intake can lead to nutritional deficiencies. Therefore, balanced and appropriate protein and energy intake is very important for disease prevention

Eating regularly

When the liver has a weaker glycogen storage capacity, three meals a day should be taken regularly with proper nutrition in order to avoid a shortage of liver glycogen

Avoid eating foods that require a long time for digestion in the middle of the night

It is recommended to take carbohydrate-based energy supplements before going to bed, and avoid eating indigestible foods that contain high fat or oil late at night, in order not to increase the burden on the digestive system

Limiting salt intake

If symptoms such as ascites and oedema are present, the recommended daily salt intake is 5-6 grams

Appropriate energy and protein intake

Excessive protein and energy intake is one of the main causes of high blood ammonia levels. On the contrary, insufficient protein and energy intake can lead to nutritional deficiencies. Therefore, balanced and appropriate protein and energy intake is very important for disease prevention

Eating regularly

When the liver has a weaker glycogen storage capacity, three meals a day should be taken regularly with proper nutrition in order to avoid a shortage of liver glycogen

Avoid eating foods that require a long time for digestion in the middle of the night

It is recommended to take carbohydrate-based energy supplements before going to bed, and avoid eating indigestible foods that contain high fat or oil late at night, in order not to increase the burden on the digestive system

Limiting salt intake

If symptoms such as ascites and oedema are present, the recommended daily salt intake is 5-6 grams

Frequently Asked Questions1

A:The regular daily dosage (150 g) of this product provides 40.5 g of protein and a total of 630 kcal. When the patient needs more protein and calories, the balance should be supplemented in the patient’s diet.

A:When a patient rejects the product due to its taste (particularly its bitterness), the dosage of the product may be reduced to approximately 0.8 kcal/mL (reconstitute one package [50 g] of the product in approximately 230 mL of water or warm water).

A:When a patient requires restriction of water intake, the dosage of the product may be increased to approximately 2 kcal/mL (reconstitute one package [50 g] of the product in approximately 80 mL of water or warm water).

A:Aminoleban ® EN powder can be taken with most food or drinks. However,
please be reminded that boiling water should not be used for reconstitution to
avoid denaturation of the protein. Fresh fruit juice should not be combined since the acidity of the fruit juices may cause gel formation.

A:Aminoleban® EN powder is generally well tolerated: abdominal distension, nausea, heartburn and abdominal pain ccasionally occur; if there is diarrhea, the dose needs to be reduced or stopped. Patients who have allergic reactions to Aminoleban® EN powder, such as rash, itching, should stop taking it.

A:People who have had an allergic reaction to any ingredient of Aminoleban® EN powder should not take it; people who are allergic to milk should also not take Aminoleban® EN powder as it contains casein as an additive. For enquiry, please consult your doctor or pharmacist.

Frequently
Asked Questions1

A:The regular daily dosage (150 g) of this product provides 40.5 g of  protein and a total of 630 kcal. When the patient needs more protein and calories, the balance should be supplemented in the patient’s diet.

A:When a patient rejects the product due to its taste (particularly its bitterness), the dosage of the product may be reduced to approximately 0.8 kcal/mL (reconstitute one package [50 g] of the product in approximately 230 mL of water or warm water).

A:When a patient requires restriction of water intake, the dosage of the product may be increased to approximately 2 kcal/mL (reconstitute one package [50 g] of the product in approximately 80 mL of water or warm water).

A:Aminoleban ® EN powder can be taken with most food or drinks. However, please be reminded that boiling water should not be used for reconstitution to avoid denaturation of the protein. Fresh fruit juice should not be combined since the acidity of the fruit juices may cause gel formation.

A:Aminoleban® EN powder is generally well tolerated: abdominal distension, nausea, heartburn and abdominal pain occasionally occur; if there is diarrhea, the dose needs to be reduced or stopped. patients who have allergic reactions to Aminoleban® EN powder, such as rash, itching, should stop
taking it.

A:People who have had an allergic reaction to any ingredient of Aminoleban® EN powder should not take it; people who are allergic to milk should also not take Aminoleban® EN powder as it contains casein as an additive. For enquiry, please consult your doctor or pharmacist.

References:
1. Aminoleban® EN Powder Hong Kong prescribing information.
2. Wolfe RR. J Int Soc Sports Nutr 2017;14:30.
3. Ichida F, et al. Acta Hepatologica Japonica 1988;29:1051-61.
4. Yamanashi Prefecture. Points of Diet Management for hepatic patient. Available from: https://www.pref.yamanashi.jp/kansensho/kansensyou/kannshikkannreshipi/documents/2.pdf (last accessed Apr 2021).

Aminoleban® EN is a registered trademark of Otsuka Pharmaceutical Co., Ltd. of Japan.

The information on this webpage only includes general information, which is only for the personal reference of those who visit this website, and does not replace the professional advice and instructions given to patients by doctors or pharmacists. For details, please consult your doctor or pharmacist. You should not rely solely on the content contained in this webpage, and we assume no responsibility or consequences for any omissions or errors in the content. Otsuka Pharmaceutical (H.K.) Limited does not endorse or recommend any products disclosed or displayed on this website, and does not make any representations or guarantees regarding any information contained. The information on this website is only applicable to people who visit this website in Hong Kong, and the information contained about the drug may be different from the drug labels of other countries.

Medical professionals should refer to the detailed prescribing information of the product registered with the Pharmacy and Poisons Board of Hong Kong
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HKOP-AMN-EN-202205-003

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Karnofsky’s performance status can be scored from Grade 0 to 10. Generally speaking, Grade 3 or higher means that the patient’s normal daily life more or less require assistance, while Grade 2 or lower means the patient’s daily life does not require assistance.

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